HYPOTHYROIDISM

Hypothyroidism

-          Congenital thyroid defects and deficiency hormone synthesis

-          Subclinical forms to myxedema an advanced form.

-          Prenatal and postnatal iodine deficiency. (Radioactive iodine).

-          Causes: Autoimmune diseases ( Hashimotos disease), decreased levels of thyroid hormones (T₃ & T₄) slows the basal metabolic rate (BMR)

x Clinical Manifestations:

1. Fatigue     2. Hair loss     3. Brittle nails      4. Dry skin      5. Hoarseness

6. Numbness and tingling of the fingers          7. Voice husky    8. Amenorrhea

9. Subnormal temperature d pulse rate   10. Gain weight (even without an increase in food intake).

-          Sever Hypothyroidism is associated with elevated serum cholesterol level atherosclerosis, coronary artery disease, poor left ventricular function.

-          Myxedema coma: sever stage of hypothyroidism, involves hypothermia, bradycardia, hypoventilation and unconsciousness and lethargy.

x Therapeutic Intervention:

1. Restore a normal metabolic state by replacing the missing hormone.
2. Pharmacologic therapy: synthetic levothyroxine (synthroid or levothroid)
3. The dosage for hormone replacement is based on the patient's serum TSH concentration.

x Diet:

$ Calorie          $ Fat             $ Cholesterol