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Spot of Heath

Spot of Heath
Showing posts with label Diseases. Show all posts
Showing posts with label Diseases. Show all posts

Tuesday, December 27, 2016

Signs and symptoms of insomnia


Signs and symptoms of insomnia                                   Home

Insomnia symptoms occur in approximately 33% to 50% of the adult population; insomnia symptoms with distress or impairment (general insomnia disorder) in 10% to 15%. Consistent risk factors for insomnia include increasing age, female sex, comorbid (medical, psychiatric, sleep, and substance use) disorders, shift work, and possibly unemployment and lower socioeconomic status.

Symptoms of Insomnia

According to guidelines from a physician group, people with insomnia have one or more of the following symptoms:

• Difficulty falling asleep at night
• Waking earlier than desired
• Still feeling tired after a night's sleep
• Daytime fatigue or sleepiness
• Irritability, depression, or anxiety
• Poor concentration and focus
• Being uncoordinated, an increase in errors or accidents
• Tension headaches (feels like a tight band around head)
• Difficulty socializing
• Gastrointestinal symptoms
• Worrying about sleeping
• Difficulty falling asleep at night
• Waking up during the night
• Waking up too early
• Not feeling well-rested after a night's sleep
• Daytime tiredness or sleepiness
• Difficulty paying attention, focusing on tasks or remembering
• Increased errors or accidents
• Ongoing worries about sleep

• Sleep for only short periods






























































References:
- http://www.mayoclinic.org/diseases-conditions/insomnia/symptoms-causes/dxc-20256961
- http://www.medicalnewstoday.com/articles/9155.php
- https://www.nhlbi.nih.gov/health/health-topics/topics/inso/signs
- https://sleepfoundation.org/insomnia/content/symptoms
- http://www.aasmnet.org/Resources/ClinicalGuidelines/040515.pdf

Thursday, December 22, 2016

Irritable Bowel Syndrome (IBS) ... Symptoms ... What not to eat and What to eat ?


Irritable bowel syndrome (IBS) ... Symptoms ... What not to eat and What to eat ?


Irritable bowel syndrome is a condition that affects the function and behavior of the intestines. Normally, the muscles lining the intestines intermittently contract and relax to move food along the digestive tract. In IBS, this pattern is disturbed, resulting in uncomfortable symptoms. More than 40 million people are affected by IBS. It is important to remember that patients with IBD can also have IBS.

Risk factor
• Age> 50 years
• Short history of symptoms
• Documented weight loss
• Nocturnal symptoms
• Male sex
• Family history of colon cancer
• Anaemia
• Rectal bleeding
• Recent antibiotic use

Symptoms
• Cramping
• Abdominal pain
• Bloating
• Gas
• Diarrhea
• Constipation


The hallmark of IBS is abdominal pain or discomfort associated with either a change in bowel habits or disordered defecation. The pain or discomfort associated with IBS is often poorly localized and may be migratory and variable. It may occur after a meal, during stress or at the time of menses. In addition to pain and discomfort, altered bowel habits are common, including diarrhea, constipation, and diarrhea alternating with constipation. Patients also complain of bloating or abdominal distension, mucous in the stool, urgency, and a feeling of incomplete evacuation. Some patients describe frequent episodes, whereas others describe long
symptom-free periods. Patients with irritable bowel frequently report symptoms of other functional gastrointestinal disorders as well, including chest pain, heartburn, nausea or dyspepsia, difficulty swallowing, or a sensation of a lump in the throat or closing of the throat. Patients with IBS are generally classified according to the type of bowel habits that accompany pain. Some patients have diarrhea-predominant symptomatology, others constipation-predominant, and still others have a combination of the two. Some patients alternate between different subgroups.
Symptoms may vary from barely noticeable to debilitating, at times within the same patient. In some patients, stress or life crises may be associated with the onset of symptoms, which may then disappear when the stress dissipates. Other patients seem to have random IBS episodes with spontaneous remissions. Still others
describe long periods of symptoms and long symptom-free periods.
In general, the symptoms of IBS wax and wane throughout life, but the majority of patients seen by physicians is 20-50 years old. In approximately 50 of patients, symptoms begin before age 35. The disorder is also recognized in children, generally appearing in early adolescence. Many patients can trace the onset of symptoms
back to childhood. The prevalence of IBS is slightly lower in the elderly, and in this patient population organic disorders must be excluded.

WHAT NOT TO EAT
According Stanford Primary Care Clinics:

FOODS'TO'AVOID
1. Raw fruit
2. Raw vegetables: (Esp. Broccoli, cabbage, Brussel sprouts, cauliflower, onions, radish, eggplant, celery).
3. Popcorn
4. Fried Foods
5. Nuts and seeds
6. Tomato Sauce, Spicy'foods
7. Mayonnaise, Miracle Whip
8. Most "fast foods" (e.g. Frenchfries, hamburgers, hotdogs, potatochips)
9. Rich foods (e.g. chocolatecake, cookies)
10. Beans (pintobeans, redbeans, chili, burritos)
11. Salads (orany foods that contain lettuce, cucumbers, etc.)
12. Whole wheat product
13. Sugarless products (candy, gum)
14. Fructos' containing products

 DRINKS'TO'AVOID:
1. Soda (esp. From a bottle)
2. Milk, Ice Cream
3. Alcohol
4. Caffeinated beverages (i.e., coffee, tea, etc.)

 MEDICINE'TO'AVOID:
1. Aspirin
2. Non - steroidal medication (i.e, Advil, ibuprofen, alleve, etc.).


WHAT TO EAT

Foods:

1. Cooked canned vegetables (except cabbage)
2. Meat, poultry and fish (not deep fried, beef Rarely).
3. Dairy-Chesse, Yougurts, etc. (Limited amount)
4. Toast, rice, muffins, bagels
5. Soup
6. Most sandwiches (turkey, chicken, bread)
7. Tofu

Drinks

1. Juice (without pulp).
2. Water
3. Iced tea

Medication
1. Acetaminophen (Tylenol)



















































































References
- http://sim.stanford.edu/resources/smg_patient_info/IRRITABLEBOWEL09-09.pdf
http://s3.gi.org/patients/gihealth/pdf/ibs.pdf
http://www.hopkinsmedicine.org/gastroenterology_hepatology/_pdfs/small_large_intestine/irritable_bowel_byndrome_ibs.pdf
http://www.ccfa.org/assets/pdfs/ibd-and-irritable-bowel.pdf
http://www.healthline.com/health/irritable-bowel-syndrome/causes-risk-factors#1


Monday, December 19, 2016

People at High Risk for Flu Complications

People at High Risk for Flu Complications                       Home

Influenza (also known as the flu) is a contagious respiratory illness caused by flu viruses. It can cause mild to severe illness, and at times can lead to death.

According (CDC, 2016). Factors that may increase your risk of developing influenza or its complications include:


 *  Age
• Asthma
• Neurological and neurodevelopmental conditions
• Blood disorders (such as sickle cell disease)
• Chronic lung disease (such as chronic obstructive pulmonary disease (COPD) and cystic fibrosis)
• Endocrine disorders (such as diabetes mellitus)
• Heart disease (such as congenital heart disease, congestive heart failure, and coronary artery disease)
• Kidney disorders
• Liver disorders
• Metabolic disorders (such as inherited metabolic disorders and mitochondrial disorders)
• Extreme obesity (with a body mass index [BMI] of 40 or more)
• People younger than 19 years of age on long-term aspirin therapy
• Weakened immune system due to disease or medication (such as people with HIV or AIDS, or cancer, or those on chronic steroids) 

Other people at high risk from the flu:
• Adults 65 years and older
• Children younger than 5 years old, but especially children younger than 2 years old
• Pregnant women and women up to 2 weeks after the end of pregnancy
• American Indians and Alaska Natives


Read More: 
- Cold or Flu
- flu Symptoms 
- What is H1N1






















































































References:
https://www.cdc.gov/flu/protect/habits.htm.











Sunday, December 11, 2016

What is causing your back pain?


What is causing your back pain?                                     Home

Eighty percent of adults will experience significant low back pain sometime during their lifetime. Low back pain usually involves muscle spasm of the supportive muscles along the spine. Also, pain, numbness and tingling in the buttocks or lower extremity can be related to the back. Most cases of back pain are not caused by serious damage or disease but by minor sprains, strains or injuries, or a pinched or irritated nerve.

• Muscle strain. The muscles of the low back provide the strength and mobility for all activities of daily living. Strains occur when a muscle is overworked or weak.
• bending awkwardly or for long periods
• slouching in chairs
• twisting awkwardly
• overstretching
• driving or sitting in a hunched position or for long periods without taking a break
• overusing the muscles - for example, during sport or repetitive movements (repetitive strain injury)
• Ligament sprain. Ligaments connect the spinal vertebrae and provide stability for the low back. They can be injured with a sudden, forceful movement or prolonged stress.
• Poor posture. Poor postural alignment (such as slouching in front of the TV or sitting hunched over a desk) creates muscular fatigue, joint compression, and stresses the discs that cushion your vertebrae. Years of abuse can cause
• Muscular imbalances such as tightness and weakness, which also cause pain.
• Age. "Wear and tear" and inherited factors may cause degenerative changes in the discs (called degenerative disc disease), and joint degeneration of the facet joints of the spine (Called degenerative joint disease). Normal aging causes decreased bone density, strength and elasticity of muscles and ligaments. These effects can be minimized by regular exercise, proper lifting and moving techniques, proper nutrition and body composition, and avoidance of smoking.
• Disc bulge. or herniation, can cause pressure on a nerve, which can radiate pain down the leg. This generally responds well to a strengthening and stretching program and rarely requires surgery.
• Other causes of low back pain include bladder / kidney infection, endometriosis, cancer, or ovarian problems
• Sciatica Back pain is sometimes linked with pains in the leg which are called sciatica.
• Inflammation and wear of the sacroiliac joint































































































References:
- Http://www.webmd.com/back-pain/guide/causes-back-pain
- Https://uhs.berkeley.edu/sites/default/files/LowBackPain.pdf
- Http://www.nhs.uk/Conditions/Back-pain/Pages/Causes.aspx
- Www.csp.org.uk/sites/files/csp/secure/7_back_pain.pdf

Friday, December 9, 2016

Depression signs and symptoms briefly

Depression signs and symptoms briefly                             Home

Sadness is only a small part of depression. Some people with
depression may not feel sadness at all. Depression has many other
symptoms, including physical ones. If you have been experiencing any of
the following signs and symptoms for at least 2 weeks, you may be
suffering from depression:
• Persistent sad, anxious, or "empty" mood
• Feelings of hopelessness, pessimism
• Feelings of guilt, worthlessness, helplessness
• Loss of interest or pleasure in hobbies and activities
• Decreased energy, fatigue, being "slowed down"
• Difficulty concentrating, remembering, making decisions
• Difficulty sleeping, early-morning awakening, or oversleeping
• Thoughts of death or suicide, suicide attempts
• Restlessness, irritability
• Persistent physical symptoms
• continuous low mood or sadness
• feeling hopeless and helpless
• having low self-esteem
• feeling tearful
• feeling irritable and intolerant of others
• having no motivation or interest in things
• finding it difficult to make decisions
• not getting any enjoyment out of life
• feeling anxious or worried
• having suicidal thoughts or thoughts of harming yourself
• moving or speaking more slowly than usual
• changes in appetite or weight (usually decreased, but sometimes increased)
• constipation
• unexplained aches and pains
• lack of energy
• low sex drive (loss of libido)
• changes to your menstrual cycle
• disturbed sleep - for example, finding it difficult to fall asleep at night or waking up very early in the morning
• Unexplained aches and pains. An increase in physical complaints such as headaches, back pain, aching muscles, and stomach pain.







Read More About Causes of Depression briefly


































References:
- https://www.nimh.nih.gov/health/publications/depression-what-you-need-to-know-12-2015/depression-what-you-need-to-know-pdf_151827.pdf.
- http://www.nhs.uk/Conditions/Depression/Pages/Symptoms.aspx.
- http://www.helpguide.org/articles/depression/depression-signs-and-symptoms.htm










Friday, May 13, 2016

What causes dizziness?


Dizziness is a term used to describe a range of sensations, such as feeling faint, woozy, weak or unsteady. Dizziness that creates the false sense that you or your surroundings are spinning or moving is called vertigo (Mayo Clinic,2015).

OR

Dizziness is the feeling of being lightheaded, woozy, or unbalanced. It affects the sensory organs, specifically the eyes and ears, so it can sometimes cause fainting. Dizziness is not a disease, but rather a symptom of various disorders (Krucik, 2015).


What causes dizziness?

- Low Blood Sugar (Hypoglycemia)
- Labyrinthitis
- Hypotension
- High blood pressure
- Meniere's Disease (Meniere's disease is a disorder that affects the inner ear)
- Abnormal Heart Rhythms
- Heart Attack
- Stroke
- Bleeding
- Hyperventilation
- Dehydration
- Heat Emergencies
- Beriberi (Beriberi is a disease caused by a vitamin B1 (thiamine) deficiency).
- Hypovolemic Shock
- Middle Ear Infection
- Vertebrobasilar Circulatory Disorders
- Cold & Flu
- Benign Positional Vertigo
- Ventricular Tachycardia
- Whiplash (Whiplash occurs when a person's head moves backward and then forward very suddenly with great force).
- Caffeine Overdose
- Paroxysmal Supraventricular Tachycardia (PSVT)
- Atrial Flutter
- Pregnancy
- Chemical Burns
- Respiratory Alkalosis
- Dizziness caused by medications
- Dizziness caused by aging:
    *Reduced capacity for exercise or activity, weakness, and                  deconditioning
* Reduced ability for the blood circulation to compensate for quickly assuming an upright position (orthostatic hypotension)
* Hardening of the arteries (arteriosclerosis)
* Neuropathy (a progressive dysfunction of the nerves that is caused by different illnesses, especially diabetes)
* Menopause
* Poor eyesight and coordination
* Dementia
- Dizziness caused by psychiatric conditions: Depression, anxiety, or panic disorder
- Dandy's syndrome is a feeling of everything bouncing up and down. It can happen to people who take an antibiotic that is toxic to the ear. It usually improves over time.























































References: 
- http://www.mayoclinic.org/diseases-conditions/dizziness/basics/definition/con-20023004

- http://www.healthline.com/symptom/dizziness

- http://www.webmd.com/first-aid/understanding-dizziness-basics

- http://www.emedicinehealth.com/dizziness/page2_em.htm

Tuesday, February 23, 2016

Signs and symptoms of appendicitis


What Is the Appendix?
The appendix is a narrow tube-shaped pouch protruding from your large intestine. It's up to six inches long and located in the lower right side of your abdomen. You do not need your appendix to live. In fact, its purpose is poorly understood.

When your appendix becomes inflamed, it's called appendicitis. The exact cause of appendicitis is not always clear. Sometimes, the appendix fills with mucus, parasites, or stool, which causes irritation. Bacteria can quickly multiply within an inflamed appendix. If it bursts, it can spread bacteria within the abdomen (peritonitis). The resulting infection can cause abscesses to form.
A ruptured appendix is a life-threatening situation (healthline, 2014).

Signs and symptoms of appendicitis may include:

1. Sudden pain that begins on the right side of the lower abdomen, Typically, symptoms begin as periumbilical or epigastric pain migrating to the right lower quadrant (RUQ) of the abdomen.

2. Sudden pain that begins around your navel and often shifts to your lower right abdomen. Some people, including children and pregnant women, may experience pain in different areas of their abdomen or on their side (health, 2014).

3. Pain that worsens if you cough, walk or make other jarring movements.

4. Nausea and vomiting.

5. Loss of appetite "anorexia"

6.Fever

7. Constipation or diarrhea

8. Abdominal Blating

* According Uptodate, 2016 In many patients, initial features are atypical or nonspecific, and can include:

● Indigestion
● Flatulence
● Bowel irregularity
● Diarrhea
● Generalized malaise

* The duration of symptoms is less than 48 hours in approximately 80% of adults but tends to be longer in elderly persons and in those with perforation. Approximately 2% of patients report duration of pain in excess of 2 weeks. A history of similar pain is reported in as many as 23% of cases, but this history of similar pain, in and of itself, should not be used to rule out the possibility of appendicitis (medscape, 2015).


* The site of your pain may vary, depending on your age and the position of your appendix. When you're pregnant, the pain may seem to come from your upper abdomen because your appendix is higher during pregnancy (mayoclinic, 2014).


* The most common complications of appendicitis are rupture, abscess, and peritonitis. and complications of appendectomy include wound infection and abscess. (medicinenet, 2015).










































































References:
- http://emedicine.medscape.com/article/773895-clinical.
- http://www.mayoclinic.org/diseases-conditions/appendicitis/basics/symptoms/con-20023582.
- http://www.healthline.com/health/digestive-health/appendicitis-emergency-symptoms#Signs&Symptoms2.
- http://www.health.com/health/gallery/0,,20552994_2,00.html.
- http://www.medicinenet.com/appendicitis/article.htm.
- http://www.uptodate.com/contents/acute-appendicitis-in-adults-clinical-manifestations-and-differential-diagnosis?source=search_result&search=appendicitis&selectedTitle=3~150.



Friday, January 29, 2016

What is Zika virus disease (Zika)?


What is Zika virus disease (Zika)?

Zika virus is an emerging mosquito-borne virus that was first identified in Uganda in 1947 in rhesus monkeys through a monitoring network of sylvatic yellow fever. It was subsequently identified in humans in 1952 in Uganda and the United Republic of Tanzania. Outbreaks of Zika virus disease have been recorded in Africa, the Americas, Asia and the Pacific.

Genre: Flavivirus
Vector: Aedes mosquitoes (which usually bite during the morning and late afternoon / evening hours)
Reservoir: Unknown (WHO, 2016).

Zika is a disease caused by Zika virus that is spread to people primarily through the bite of an infected Aedes species mosquito. The most common symptoms of Zika are fever, rash, joint pain, and conjunctivitis (red eyes). The illness is usually mild with symptoms lasting for several days to a week (CDC. 2016).

What are the symptoms of Zika?

according (CDC, 2016) About 1 in 5 people infected with Zika will get sick. For people who get sick, the illness is usually mild. For this reason, many people might not realize they have been infected.


The most common symptoms of Zika virus disease are fever, rash, joint pain, or conjunctivitis (red eyes). Symptoms typically begin 2 to 7 days after being bitten by an infected mosquito
1. Zika virus infection is characterized by low grade fever (less than 38.5 ° C).
2. arthralgia, notably of small joints of hands and feet, with possible swollen joints.
3. myalgia
4. headache, retro-ocular headaches
5. conjunctivitis
6. rash
7. post-infection asthenia which seems to be frequent.



The incubation period (the time from exposure to symptoms) of Zika virus disease is not clear, but is likely to be a few days (2-7 days).


How is Zika transmitted?

Zika virus is primarily transmitted to humans through bites from Aedes mosquitoes, which often live around buildings in urban areas and are usually active during daylight hours (peak biting activity occurs in early mornings and late afternoons).

Some evidence suggests Zika virus can also be transmitted to humans through blood transfusion, perinatal transmission and sexual transmission. However, these modes are very rare. It can also be transmitted from a pregnant mother to her baby during pregnancy or around the time of birth. We do not know how often Zika is transmitted from mother to baby during pregnancy or around the time of birth.

Zika virus disease outbreaks were reported for the first time from the Pacific in 2007 and 2013 (Yap and French Polynesia, respectfully), and in 2015 from the Americas (Brazil and Colombia) and Africa (Cape Verde). In addition, more than 13 countries in the Americas have reported sporadic Zika virus infections indicating rapid geographic expansion of Zika virus (WHO, 2016).

See image Down for Countries where the Zika Virus is spreading.

Who is at risk of being infected?

Anyone who is living in or traveling to an area where Zika virus is found who has not already been infected with Zika virus is at risk for infection, including pregnant women.


Prevention

Mosquitoes and their breeding sites pose a significant risk factor for Zika virus infection. Prevention and control relies on reducing mosquitoes through source reduction (removal and modification of breeding sites) and reducing contact between mosquitoes and people.

This can be done by using insect repellent; wearing clothes (preferably light-coloured) that cover as much of the body as possible; using physical barriers such as screens, closed doors and windows; and sleeping under mosquito nets. It is also important to empty, clean or cover containers that can hold water such as buckets, flower pots or tyres, so that places where mosquitoes can breed are removed.

Special attention and help should be given to those who may not be able to protect themselves adequately, such as young children, the sick or elderly.

During outbreaks, health authorities may advise that spraying of insecticides be carried out. Insecticides recommended by the WHO Pesticide Evaluation Scheme may also be used as larvicides to treat relatively large water containers.

Travellers should take the basic precautions described above to protect themselves from mosquito bites

Treatment

Zika virus disease is usually relatively mild and requires no specific treatment. People sick with Zika virus should get plenty of rest, drink enough fluids, and treat pain and fever with common medicines. If symptoms worsen, they should seek medical care and advice. There is currently no vaccine available.

according (CDC, 2016)
There is no vaccine or specific medicine to treat Zika virus infections.

Treat the symptoms:


  1. Get plenty of rest.
  2. Drink fluids to prevent dehydration.
  3. Take medicine such as acetaminophen to reduce fever and pain.
  4. Do not take aspirin or other non-steroidal anti-inflammatory drugs.
  5. If you are taking medicine for another medical condition, talk to your healthcare provider before taking additional medication











Related to

Read More about What is H1N1 "Swine" flu?


























































































































Refernceses 
- http://www.who.int/mediacentre/factsheets/zika/en/
- http://www.wpro.who.int/mediacentre/factsheets/fs_05182015_zika/en/
- http://www.cdc.gov/zika/disease-qa.html
- http://www.health.govt.nz/our-work/diseases-and-conditions/zika-virus
- http://waer.org/post/upstate-infectious-disease-expert-zika-virus-spreading-not-threat-cny



Saturday, January 16, 2016

How does the H1N1 flu differ from the seasonal flu?



How does the H1N1 flu differ from the seasonal flu?

     Flu (influenza) viruses are divided into three broad categories: influenza A, B or C. Influenza A is the most common type. H1N1 flu is a variety of influenza A.

Even though the H1N1 virus and the seasonal flu are the same in many ways, they are two different types of influenza.

What Makes Them the Same?
• Both flu 'symptoms include fever, body aches, headache, sore throat, cough,
runny / stuffy nose, chills, fatigue and possibly diarrhea and / or vomiting.
• Both viruses are spread mainly from person-to-person through coughing or
sneezing. Sometimes people can get the flu by touching something with flu
viruses on it and then touching their eyes, mouth or nose.
• Both types of flu are treated using fever reducing medication, plenty of fluids,
antivirals and rest.

What Makes Them Different?

  •  The H1N1 virus is new, so not as many people are immune to it.
  •  Unlike seasonal flu, people 65 and over are less likely to get the H1N1 flu.
  •  The CDC reports the H1N1 virus has affected more people younger than 25 years old vs. the older population.
  • Unlike seasonal flu, swine flu can be passed from person to person in warm weather and cold weather.
  • Seasonal flu, which peaks during late December through early March, is most efficiently passed from person to person through droplets in the air when the weather is cold. "When it warms up in the spring, transmission stops
  • Another significant way that the viruses differ is that in a third of the cases that have come to medical attention H1N1 affects the gastrointestinal tract as well as the respiratory system. "That's just something that we do not see in seasonal flu, which is really a respiratory virus," (www.newyorkpresbyterianhospital.com, 2009).
  • Pregnant women are dramatically more affected by H1N1.


  • Seasonal fluTypical influenza viruses infect the cells lining the main airway and nasal tract, according to Earl Brown, a virologist at the University of Ottawa. H1N1The virus also infects the airway, but in some individuals, it continues to move down and infect the lungs. It's "very unusual" for seasonal flu viruses to infect lungs, Dr. Brown said. The H1N1 virus causes lung infection much more often and "more completely," he said, which is why some people have ended up in intensive care units or even dying from complications of the virus. (www.theglobeandmail.com, 2012). 













  • Read More What is H1N1 "Swine" flu?

    Read More  Signs and Symptoms








































































































































    References
    - http://www.stfranciscare.org/uploadedFiles/H1N1_vs_Seasonal_web_final.pdf
    - http://www.newyorkpresbyterianhospital.com/enews/whats-the-difference-h1n1-seasonal-flu.html
    - http://www.mayoclinic.org/diseases-conditions/swine-flu/expert-answers/influenza-a/faq-20058309
    - http://www.theglobeandmail.com/life/health-and-fitness/health/conditions/h1n1-v-seasonal-flu-how-to-tell-the-difference/article4290774/
    - http://www.mtoliveboe.org/cmsAdmin/uploads/cold_flu_swine_flu-1_001.pdf


    Sunday, January 10, 2016

    What is H1N1 "Swine" flu?





    What is H1N1 flu?
    This is an influenza virus that had never been identified as a cause of infections in people before the current H1N1 pandemic. Genetic analysis of this virus have shown that it originated from animal influenza viruses and is unrelated to the human seasonal H1N1 viruses that have been in general circulation among people since 1977 (WHO, 2009).

    H1N1 is a flu virus. When it was first detected in 2009, it was called "swine flu" because the virus was similar to those found in pigs.

    The H1N1 virus is currently a seasonal flu virus found in humans. Although it also circulates in pigs, you can not get it by eating properly handled and cooked pork or pork products.

    According Medline plus site; Swine flu is an infection caused by a virus. It's named for a virus that pigs can get. People do not normally get swine flu, but human infections can and do happen. In 2009 a strain of swine flu called H1N1 infected many people around the world.

    The virus is contagious and can spread from human to human. Symptoms of swine flu in people are similar to the symptoms of regular human flu and include fever, cough, sore throat, body aches, headache, chills and fatigue.

    People who have it can spread it one day before they have any symptoms and as many as 7 days after they get sick. Kids can be contagious for as long as 10 days.

    Like the regular flu, swine flu can lead to more serious problems including pneumonia, a lung infection, and other breathing problems. And it can make an illness like diabetes or asthma worse. If you have symptoms like shortness of breath, severe vomiting, pain in your belly or sides, dizziness, or confusion, call your doctor or Emergency right away.

    What are the symptoms of H1N1 flu?

    What are the incubation flu?
    based of CDC; In general, the incubation period for influenza is estimated to range from 1 to 4 days with an average of 2 days. Influenza virus shedding (the time during which a person might be infectious to another person) begins the day before illness onset and can persist for 5 to 7 days, although some persons may shed virus for longer periods, particularly young children and severely immunocompromised persons. The amount of virus shed is greatest in the first 2-3 days of illness and appears to correlate with fever, with higher amounts of virus shed when temperatures are highest.

    Transmission
    Spread of this pandemic influenza A (H1N1) virus is thought to be happening in the same way that seasonal flu spreads. Flu viruses are spread mainly from person to person through coughing or sneezing of people with influenza. Sometimes people may become infected by touching something with flu viruses on it and then touching their mouth or nose.
    Since pandemic influenza A [H1N1] is not directly associated pigs the issue of transmission through consumption of pork does not arise.

    How long does the H1N1 virus last outside the body? 
    Influenza viruses can survive on environmental surfaces like kitchen counters and door knobs, for up to 2-8 hours.

    Are There Tests for Swine Flu?
    Yes. Without one it's hard to tell whether you have swine flu or seasonal flu, because most symptoms are the same. If you have swine flu, you may be more likely to feel sick and your stomach and throw up than with regular flu. But a lab test is the only way to know. Even a rapid flu test you can get in your doctor's office will not tell you for sure.


    Read More about Influenza Tests



    high risk for life-threatening problems from swine flu, such as:

    - Children under 5 years old
    - People 65 or older
    - Children and teens (under age 18) who are getting long-term aspirin therapy and who might be at risk for Reye's syndrome after being infected with swine flu. Reye's syndrome is a life-threatening illness linked to aspirin use in children.
    - Pregnant women
    - Adults and children with chronic lung, heart, liver, blood, nervous system, neuromuscular, or metabolic problems
    - Adults and children who have weakened immune systems (including those who take medications to suppress their immune systems or who have HIV)

    According (UpToDate; 2015); Indications - Based on the CDC guidelines, prompt initiation of antiviral therapy was recommended for children, adolescents, or adults with suspected or confirmed influenza infection and any of the following features [5,19]:

    ● Illness requiring hospitalization
    ● Progressive, severe, or complicated illness, regardless of previous health status
    It was also recommended that early treatment be considered in patients with suspected or confirmed influenza infection who were at high risk for complications including:

    ● Children <5 years of age, particularly those <2 years of age
    ● Adults ≥65 years of age
    ● Pregnant women and women up to two weeks postpartum (including those who have had pregnancy loss)
    ●Individuals with certain medical conditions:
    Individuals with chronic medical conditions including:
    • Pulmonary disease, including asthma (particularly if systemic glucocorticoids have been required during the past year)
    • Cardiovascular disease, except isolated hypertension
    • Active malignancy
    • Chronic renal insufficiency
    • Chronic liver disease
    • Diabetes mellitus
    • Hemoglobinopathies, such as sickle cell disease
    • Immunosuppression, including HIV infection (particularly if CD4 <200 cells / microL), organ and hematopoietic cell transplantation, inflammatory disorders treated with immunosuppressants
    • Any neurologic condition that can compromise handling of respiratory secretions (eg, cognitive dysfunction, spinal cord injuries, seizure disorders, neuromuscular disorders)
    ● Individuals who are morbidly obese (body mass index [BMI] ≥40)

    Complication 

    Influenza complications include:

    - Worsening of chronic conditions, such as heart disease and asthma
    Pneumonia
    - Neurological signs and symptoms, ranging from confusion to seizures
    - Respiratory failure

    How Is It Treated?
    Some of the same antiviral drugs that are used to treat seasonal flu also work against H1N1 swine flu. Oseltamivir (Tamiflu), peramivir (Rapivab), and zanamivir (Relenza) seem to work best, although some kinds of swine flu do not respond to oseltamivir.

    These drugs can help you get well faster. They can also make you feel better. They work best when you take them within 48 hours of the first flu symptoms, but they can help even if you get them later on.

    Antibiotics will not do anything for you. That's because flu is caused by a virus, not bacteria.

    According medscape, 2014 site; H1N1 Influenza (Swine Flu) Treatment & Management
    Medical Care
    Treatment is largely supportive and consists of bedrest, increased fluid consumption, cough suppressants, and antipyretics and analgesics (eg, acetaminophen, nonsteroidal anti-inflammatory drugs) for fever and myalgias. Severe cases may require intravenous hydration and other supportive measures. Antiviral agents may also be considered for treatment or prophylaxis (see Medication).
    Patients should be encouraged to stay home if they become ill, to avoid close contact with people who are sick, to wash their hands often, and to avoid touching their eyes, nose, and mouth. The CDC recommends the following actions when human infection with H1N1 influenza (swine flu) is confirmed in a community :
    Patients who develop flu like illness (ie, fever with either cough or sore throat) should be strongly encouraged to self-isolate in their home for 7 days after the onset of illness or at least 24 hours after symptoms have resolved, whichever is longer.
    To seek medical care, patients should contact their health care providers to report illness (by telephone or other remote means) before seeking care at a clinic, physician's office, or hospital.
    Patients who have difficulty breathing or shortness of breath or who are believed to be severely ill should seek immediate medical attention.
    If the patient must go into the community (eg, to seek medical care), he or she should wear a face mask to reduce the risk of spreading the virus in the community when coughing, sneezing, talking, or breathing. If a face mask is unavailable, ill persons who need to go into the community should use tissues to cover their mouth and nose while coughing.
    While in home isolation, patients and other household members should be given infection control instructions, including frequent hand washing with soap and water. Use alcohol-based hand gels (containing at least 60% alcohol) when soap and water are not available and hands are not visibly dirty. Patients with H1N1 influenza should wear a face mask when within 6 feet of others at home.












    Read More about Influenza Tests













































































































    References 
    - https://www.nlm.nih.gov/medlineplus/h1n1fluswineflu.html
    - http://www.webmd.com/cold-and-flu/flu-guide/h1n1-flu-virus-swine-flu
    - http://www.cdc.gov/h1n1flu/vaccination/
    - http://www.uptodate.com/contents/treatment-and-prevention-of-pandemic-h1n1-influenza-swine-influenza?source=search_result&search=h1n1&selectedTitle=1~86
    - http://www.who.int/csr/disease/swineflu/frequently_asked_questions/about_disease/en/
    - http://www.flu.gov/about_the_flu/h1n1/
    - http://emedicine.medscape.com/article/1807048-treatment
    - http://www.mayoclinic.org/diseases-conditions/swine-flu/basics/complications/con-20034916
    http://www.anejo.eu/wp-content/uploads/2013/03/CH5236.jpg
    - http://en.trend.az/iran/society/2465878.html
    - http://www.epid.gov.lk/web/attachments/article/146/Latest_fact_sheet_H1N1_Influenza.pdf
    - https://www.cdph.ca.gov/HealthInfo/h1n1flufaqs/Pages/H1N1fluFAQs-03-Prevention.aspx

    Saturday, January 9, 2016

    Risk factors for Deep vein thrombosis "DVT"



    Deep vein thrombosis occurs when a blood clot forms in the veins that are deep in your body, often in your legs. Blood clots can be caused by anything that prevents your blood from circulating normally or clotting properly.

    Deep vein thrombosis (DVT) and acute pulmonary embolism (PE) are two manifestations of the same disorder, venous thromboembolism (VTE). DVT of the lower extremity is subdivided into two categories:
    *  Distal (calf) vein thrombosis, in which thrombus remain confined to the deep calf veins
    *  Proximal vein thrombosis, in which thrombosis involves the popliteal, femoral, or iliac veins


    Risk factors for DVT

    ● History of immobilization or prolonged hospitalization / bed rest.
    In hospital:
      - you are having an operation that takes longer than 90 minutes, or 60 minutes if the operation is on your leg, hip or abdomen.
      - you are having an operation for an inflammatory or abdominal condition, such as appendicitis
      - you are confined to a bed, unable to walk, or spending a large part of the day in a bed or chair for at least three days.
    - A personal or family history of deep vein thrombosis or pulmonary embolism (PE). If you or someone in your family has had DVT or PE before, you're more likely to develop DVT.
    ● Recent surgery
    ● Obesity
    Being overweight increases the pressure in the veins in your pelvis and legs.
    ● Prior episode (s) of venous thromboembolism
    ● Lower extremity trauma
    ● Malignancy
    ● Use of oral contraceptives or hormone replacement therapy
    ● Pregnancy or postpartum status
    Pregnancy increases the pressure in the veins in your pelvis and legs. Women with an inherited clotting disorder are especially at risk. The risk of blood clots from pregnancy can continue for up to six weeks after you have your baby.

    ● Stroke
    ● Smoking;  affects blood clotting and circulation, which can increase your risk of DVT
    ● Age. Being over age 60 increases your risk of DVT, though it can occur at any age.







    According (UpToDate site, 2016); Risk factors (causes) for the development of venous thrombosis:


    Inherited thrombophilia:

    Factor V Leiden mutation
    Prothrombin gene mutation
    Protein S deficiency
    Protein C deficiency
    Antithrombin (TAT) deficiency
    Rare disorders
    Dysfibrinogenemia

    Acquired disorders:

    Malignancy
    Presence of a central venous catheter
    Surgery, especially orthopedic
    Trauma
    Pregnancy
    Oral contraceptives
    Hormone replacement therapy
    Tamoxifen, Thalidomide, Lenalidomide
    Immobilization
    Congestive failure
    Antiphospholipid antibody syndrome
    Myeloproliferative disorders
    Polycythemia vera
    Essential thrombocythemia
    Paroxysmal nocturnal hemoglobinuria
    Inflammatory bowel disease
    Nephrotic syndrome


    According (CDC site, 2015); Following is a list of factors that increase the risk of developing DVT

    ● Injury to a vein, often caused by:
    Fractures,
    Severe muscle injury, or
    Major surgery (particularly involving the abdomen, pelvis, hip, or legs).
    ● Slow blood flow, often caused by:
    Confinement to bed
    (eg, due to a medical condition or after surgery);
    Limited movement (eg, a cast on a leg to help heal an injured bone);
    Sitting for a long time, especially with crossed legs; or
    Paralysis.
    ● Increased estrogen, often caused by:
    Birth control pills
    Hormone replacement therapy, sometimes used after menopause
    Pregnancy, for up to 6 weeks after giving birth
    ● Certain chronic medical illnesses, such as:
    Heart disease
    Lung disease
    Cancer and its treatment
    Inflammatory bowel disease (Crohn's disease or ulcerative colitis)
    ● Other factors that increase the risk of DVT include:
    Previous DVT or PE
    Family history of DVT or PE
    Age (risk increases as age increases)
    Obesity
    A catheter located in a central vein
    Inherited clotting disorders

























































































































    References:
    - http://www.uptodate.com/contents/approach-to-the-diagnosis-and-therapy-of-lower-extremity-deep-vein-thrombosis?source=search_result&search=dvt&selectedTitle=1~150 
    - http://www.nhs.uk/Conditions/Deep-vein-thrombosis/Pages/Causes.aspx
    - http://www.mayoclinic.org/diseases-conditions/deep-vein-thrombosis/basics/causes/con-20031922
    - http://www.cdc.gov/ncbddd/dvt/facts.html
    - http://www.parkhurstexchange.com/clinical-reviews/apr11/deep-vein-thrombosis-in-the-elderly


    Friday, January 8, 2016

    G6PD .. Drugs that should be avoided


    Glucose-6-phosphate dehydrogenase deficiency is a genetic disorder that occurs most often in males. This condition mainly affects red blood cells, which carry oxygen from the lungs to tissues throughout the body. In affected individuals, a defect in an enzyme called glucose-6-phosphate dehydrogenase causes red blood cells to break down prematurely. This destruction of red blood cells is called hemolysis.

    OR

    G6PD Deficiency is a hereditary abnormality in the activity of an erythrocyte (red blood cell) enzyme. This enzyme, glucose-6-phosphate dehydrogenase (G-6-PD), is essential for ensuring a normal life span for red blood cells, and for oxidizing processes. This enzyme deficiency may provoke the sudden destruction of red blood cells and lead to hemolytic anemia with jaundice following the intake of fava beans, certain legumes and various drug.






    For see Drugs that should be avoided - Official List Click Here


    For see Gene (G6PD: glucose-6-phosphate dehydrogenase) Click Here























































































































































































    References
    - http://ghr.nlm.nih.gov/condition/glucose-6-phosphate-dehydrogenase-deficiency
    - http://www.g6pd.org/g6pddeficiency.aspx
    - http://www.ncbi.nlm.nih.gov/gene/2539